Projects

Featured projects ongoing or completed by Dr. Ay.

3D Nucleome Tutorial at ACM-BCB 2015

3D Nucleome Tutorial at ACM-BCB 2015

Computational Analysis and Modeling of Chromatin Spatial Organization

Fit-Hi-C: Statistical confidence estimation for Hi-C data

Fit-Hi-C: Statistical confidence estimation for Hi-C data

Fit-Hi-C is a tool for assigning statistical confidence estimates to intra-chromosomal contact maps produced by genome-wide genome architecture assays such as Hi-C.

P. falciparum 3D genome organization

P. falciparum 3D genome organization

Three-dimensional modeling of the P. falciparum genome during the erythrocytic cycle reveals a strong connection between genome architecture and gene expression

P. falciparum epigenetic gene regulation

P. falciparum epigenetic gene regulation

The third dimension of epigenetic gene regulation in the malaria parasite Plasmodium falciparum.

DNase Hi-C assay

DNase Hi-C assay

Fine-scale chromatin interaction maps reveal the cis-regulatory landscape of lincRNA genes in human cells.

Epigenomics Session at PSB 2013

Epigenomics Session at PSB 2013

Epigenomics Session. Pacific Symposium on Biocomputing 2013